Gonorrhoea in the chimpanzee. Serological testing.

Gonorrhoea in the chimpanzee. Serological testing.

This laboratory, with a special interest in the serodiagnosis of gonorrhoea, has become active in all aspects of serological testing of animal models as well as humans. Lucas, Chandler, Martin, and Schmale (1971) established the chimpanzee as the first animal model for Neisseria gonorrhoeae. They infected four male chimpanzees with human urethral exudates containing N. gonorrhoeae. Brown, Lucas...

A comparison of serological tests for the diagnosis of gonorrhoea.

Appropriate serological testing in pregnancy.

We read with interest the recent report by Garner et al. [l], in which anti-E was detected early in pregnancy solely through the use of enzymetreated red blood cells (RBC). The serological reactivity of this anti-E changed dramatically during pregnancy; the antibody became detectable by the indirect antiglobulin test, and at 37 weeks’ gestation had a titer of 512. Delivery at 40 weeks’ gestatio...

Combination therapy for gonorrhoea: in vitro synergy testing.

OBJECTIVES Antimicrobial resistance in Neisseria gonorrhoeae is an increasing problem worldwide and combinations of antimicrobial agents have been recommended to delay the onset of treatment failures. The objective of this study was to obtain in vitro data on the activity of current (ceftriaxone or cefixime plus azithromycin) and alternative (gentamicin plus azithromycin) regimens. METHODS A ...

Chimpanzee (Pan troglodytes) Counting in a Computerized Testing Paradigm